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Date: 5th July 2005
Title: CMC Biopharmaceuticals A/S and Syngenta Biopharma enter into umbrella agreement


CMC Biopharmaceuticals A/S (CMC), a Copenhagen-based contract manufacturing organization, announced today that they have entered into an umbrella agreement with Syngenta Biopharma, a business unit of the Swissbased agribusiness Syngenta, for the development and cGMP manufacture of a number of Syngenta's biopharmaceutical products. Financial terms were not disclosed.

Mads Laustsen, CEO of CMC, stated: "This agreement demonstrates the flexibility of CMC's multi-product facility providing services from early development to commercial cGMP compliant manufacture. CMC is manufacturing cGMP material for several companies and Syngenta's project pipeline fits well into our project portfolio."

Commenting on the agreement, Antony Blanc, Head of Syngenta Biopharma, said: "In CMC we have found a dynamic and experienced partner with whom to collaborate closely in process development and the manufacture of our most advanced microbially produced therapeutics for clinical studies."

About CMC Biopharmaceuticals A/S
Based in Copenhagen, Denmark, CMC is a contract development and manufacturing organization for biopharmaceutical products, with sales offices located in the UK and the US. CMC specializes in process and analytical development and the scale-up and cGMP manufacture of biological Active Pharmaceutical Ingredients for pre-clinical and clinical trials. Its state of the art facility has been designed for the in-market supply of these products including therapeutic proteins and monoclonal antibodies. The company is approved by the EMEA and holds a European Manufacturing Authorization.

About Syngenta
Syngenta is a world-leading agribusiness committed to sustainable agriculture through innovative research and technology. The company is a leader in crop protection, and ranks third in the highvalue commercial seeds market. Sales in 2004 were approximately $7.3 billion. Syngenta employs some 19,000 people in over 90 countries. Syngenta is listed on the Swiss stock exchange (SYNN) and in New York (SYT). Further information is available at www.syngenta.com.

Syngenta has set-up a dedicated biopharma unit (www.syngenta.com/biopharma) to apply its in-house capabilities and infrastructure to the development of biopharmaceuticals. The biopharma group works with trusted partners within flexible models to ensure maximum value. Successful projects have been initiated with partners including Diversa Corporation, Affimed Therapeutics, SemBioSys Genetics Inc., and the National Jewish Medical and Research Center.

Source: CMC Biopharmaceuticals A/S
Contact: Shiva Khalafpour
VP Business Development Europe
Phone: +44 (0)1483 832860
e-mail: sk@cmcbio.com
Website : www.cmcbio.com

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